Author Topic: Found some reagent ! What experiment can i do with it ? (Read 175 times)

Alchemyst · « **on:** May 16, 2011, 11:21:51 PM »

Hi,
I have found Some Triethylenetetramine , Cyclohexanone and Styrene
Can the TETA replace Ethylenediamine in a Birch-like reaction ?
What experiment can i do with this chemical ?
Thanks bye

Sedit · « **Reply #1 on:** May 16, 2011, 11:35:41 PM »

TETA will not work in a Birch reduction I don't believe.

Perhaps a fun experiment would be to Epoxidize styrene thru various methods and allow it to undergo ammonolysis with (aq)NH₃ to yeild 2-amino-1-phenylethanol. Surely one could think of something fun to do with that.

psychexplorer · « **Reply #2 on:** May 16, 2011, 11:50:27 PM »

Not sure about the TETA, but the cyclohexanone and styrene could be loads of fun.

Tsathoggua · « **Reply #3 on:** May 17, 2011, 04:05:06 PM »

Could use the cyclohexanone for production of ethynylcyclohexanol, a fairly potent sedative, structurally most similar to some of the oldschool downers such as ethchlorvynol, and in a similar vein to the latter, 2-methyl-butan-2-ol, and the like, as far as action goes.

React with sodium acetylide (produced by solvating Na metal in a suitable amine, saturated with acetylene gas. Liquid ammonia would definately work, but seeing as it takes the role of a solvent only, I believe EDA would probably work. Not too familiar with TETA but I wouldn't be surprised, followed by slow! addition of metallic sodium or potassium. Cessation of the acetylene flow into the amine before the addition of cyclohexanone is complete apparently encourages the formation of ethynylcyclohexanediol.

I bet you could use calcium carbide also, avoiding the use of an amine solvent for the production of the acetylide, CaC2 is pretty cheap.

Easier in practise, avoiding the use of liquid NH3, or other nasty amines, would be the simpler reaction of the enol tautomer of cyclohexanone (using NaOMe) with acetylene gas.

atara · « **Reply #4 on:** May 21, 2011, 01:11:31 AM »

Quote from: Sedit on May 16, 2011, 11:35:41 PM

TETA will not work in a Birch reduction I don't believe.

Perhaps a fun experiment would be to Epoxidize styrene thru various methods and allow it to undergo ammonolysis with (aq)NH₃ to yeild 2-amino-1-phenylethanol. Surely one could think of something fun to do with that.

aminorex

Sedit · « **Reply #5 on:** May 21, 2011, 05:53:44 PM »

Hmmmm... maybe

Also consider Everlastings post on the conversion of Styrene to Phenylacetic acid thru the dichlorination of styrene and hydrolysis of the product.

Alchemyst · « **Reply #6 on:** May 27, 2011, 06:40:21 PM »

Thanks for your reply,

1. I asked about TETA to remplace Ethylenediamine in birch like reaction beacause i've read this on wikipedia:

Quote

Triethylenetetramine

IUPAC name :
N,N'-bis(2-aminoethyl)ethane-1,2-diamine

Other names :
Trientine

Identifiers :
CAS number : 112-24-3

Properties

Molecular formula   : C6H18N4
Molar mass   : 146.23392
Melting point : 12 °C, 285 K, 54 °F
Boiling point    : 266-267 °C, 539-540 K, 511-513 °F
Solubility in water : Miscible
Data are given for materials in their standard state (at 25 °C, 100 kPa)

Triethylenetetramine, abbreviated TETA and trien, is an organic compound with the formula [CH2NHCH2CH2NH2]2. This oily liquid is colourless but, like many amines, assumes a yellowish color due to impurities resulting from air-oxidation. It is soluble in polar solvents and exhibits the reactivity typical for amines. The branched isomer N(CH2CH2NH2)3 and the cyclic triamine (CH2CH2NH)3 also comprise commercial samples of TETA.

Production

Triethylenetetramine is prepared by heating ethylenediamine or ethanolamine/ammonia mixtures over an oxide catalyst. This process gives a variety of amines, which are separated by distillation and sublimation.[1]

Uses[/u]

The reactivity and uses of TETA are similar to those for the related polyamines ethylenediamine and diethylenetriamine. It was primarily used as a crosslinker ("hardener") in epoxy curing.[1]

Chemistry

Triethylenetetramine is a tetradentate ligand in coordination chemistry, where it is referred to as trien.[2] Octahedral complexes of the type M(trien)Cl3 can adopt several diastereomeric structures, most of which are chiral.[3] The hydrochloride salt, referred to as trientine hydrochloride, is a chelating agent and has been discussed for the removal of copper in the treatment of Wilson's disease.[4]

2. And some guy's said that i can use cyclohexanone for lednicer's compound but i don't know what they are and the guys haven't answered to my message so if someone can explain to me if it's possible and what are the Lednicer' compound ?

3.

Quote from: Sedit on May 16, 2011, 11:35:41 PM

Perhaps a fun experiment would be to Epoxidize styrene thru various methods and allow it to undergo ammonolysis with (aq)NH₃ to yeild 2-amino-1-phenylethanol. Surely one could think of something fun to do with that.

Can 2-amino-1-phenylethanol be reacted with KOCN like PPA For 4-MAR

If someone have any other ideas

Thanks

Tsathoggua · « **Reply #7 on:** May 27, 2011, 07:22:25 PM »

Daniel Lednicer is a guy who has done a lot of work on synthetic opioids

Those known as 'lednicer opioids' aren't ones to fuck about with, extremely potent, perhaps 6-7 more so than fentanyl.

'bromadol' and C8813 are examples. Potency is at a level where if you screw up, and inhale some floating particulates, then you are going to pull a bluey fast. And so is your rescuer if you have one, if they just charge in without protective equipment.

These, like the fentanyls will cause rapid tachyphylaxis. Not sure what the therapeutic index is like, or the dose response curve. But I do know, that they are fucking potent.

http://en.wikipedia.org/wiki/C-8813

Alchemyst · « **Reply #8 on:** May 29, 2011, 08:49:43 PM »

ok i think' i want not plays with this sort of Compound, too dangerous

Tsathoggua · « **Reply #9 on:** May 30, 2011, 09:38:44 AM »

Good idea. Not the sort of compound you can make without a bunnysuit and live to tell the tale.

Would make excellent tactical chemical weapons in certain circumstances though, look at the russian use of KOLOKOL-1, pumped into a theatre in chechnya during a terrorist siege, dissolved in something like halothane. Few left conscious, the russki special forces just walked in there and shot the terrorists dead while they were out cold or nearly so.

Most likely some potent fentanyl derivative in that case.

Author Topic: Found some reagent ! What experiment can i do with it ? (Read 175 times)

Alchemyst

Found some reagent ! What experiment can i do with it ?

Sedit

Re: Found some reagent ! What experiment can i do with it ?

psychexplorer

Re: Found some reagent ! What experiment can i do with it ?

Tsathoggua

Re: Found some reagent ! What experiment can i do with it ?

atara

Re: Found some reagent ! What experiment can i do with it ?

Sedit

Re: Found some reagent ! What experiment can i do with it ?

Alchemyst

Re: Found some reagent ! What experiment can i do with it ?

Tsathoggua

Re: Found some reagent ! What experiment can i do with it ?

Alchemyst

Re: Found some reagent ! What experiment can i do with it ?

Tsathoggua

Re: Found some reagent ! What experiment can i do with it ?