what i was describibg was a way of synthesizing amides of lysergic acid skipping lysergic acid hydrolysis by going straight to the ester it was something i stumbled upon last year and i thought how convenient.
basically like i said the ester comes out clean and quantitative and you react that with what ever amine you want to in alcohol.
they suggest a sealed vessel and heat but my intuition tells me better yeilds would be had with time and stp.
60% is what they got it is'nt pyop but damn easy when you think about it.
the isomer ratio coming out of the pot was 80% d 20% l
i would just chromatograph the end product but that's because i'm lazy.
lemme find the patent there's even czech patents that use the pentachlorphenyl ester and get stellar yeilds at room temperature
basically like i said the ester comes out clean and quantitative and you react that with what ever amine you want to in alcohol.
they suggest a sealed vessel and heat but my intuition tells me better yeilds would be had with time and stp.
60% is what they got it is'nt pyop but damn easy when you think about it.
the isomer ratio coming out of the pot was 80% d 20% l
i would just chromatograph the end product but that's because i'm lazy.
lemme find the patent there's even czech patents that use the pentachlorphenyl ester and get stellar yeilds at room temperature
, but seriously can we talk about the methyl ester method? I think it may have been using during the total synthesis of lysergic acid, can't find the paper. 
lysergic.acid.woodward.pdf