Author Topic: Split topic: Purification of morphine sulfate from binding agents  (Read 29 times)

reDEEMed

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Split topic: Purification of morphine sulfate from binding agents
« on: August 26, 2011, 11:32:54 PM »
Okay, after some serious fucking with washing these pills I can say that a water wash alone will not circumvent the contin matrix, no way no how. I've tried several methods and the one that works the best, for MS contin anyway, is as follows.

Wash the pigment off or suck off, lol. Gently bake the pills in a flask, this makes crushing them sooooo fucking easy. Mix the dry cooled powder with some 1 M Hcl and allow it to sit a few minutes until its almost all dissolved. Dilute up to around 70ml (using 250mg of powder) with distilled water. Throw that in a 250ml erlenmeyer with 85ml of mineral spirits and 15ml of toluene (I'm sure this could be any number of things). Heat to 80C with stirring. Dump hot in to sep funnel and drain the aqueous layer in to a dish with a fan blowing on it.  Evaporate and scrape it up.

It's still dirty at this point, but not very, plus it's no longer sulfate, it's HCl. This was based on a post made by a guy named MobiusDick, who enjoys some amount of internet fame for his expertise in circumventing these time release mechanisms. I read MSDS's for two fucking days and I'm telling you that water alone will get you jelly everytime. I was able to breakdown the jelly with a lot of heat but all in all it took way more effort for a much smaller return doing it that way.

Now all you need to do is get your procedure ironed out, Hypnos.
"Ego is a structure that is erected by a neurotic individual who is a member of a neurotic culture against the facts of the matter. And culture, which we put on like an overcoat, is the collectivized consensus about what sort of neurotic behaviors are acceptable."
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hypnos

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Re: Split topic: Purification of morphine sulfate from binding agents
« Reply #1 on: September 08, 2011, 05:58:28 AM »
 Now that makes A LOT of sense to me,
  I'm not sure why this post is here, BUT ....Yeah matey A VERY good Idea, and as the Hcl satl is fine for the purpose/s

Great Tip 8)--one thing I would use more water as M is-soluble at only 0.6gm/ml in water.....I think your mates yields will improve by doing so.....

 Thanx mate

Happy Hyppy
« Last Edit: September 08, 2011, 06:42:57 AM by hypnos »
"the two things you can give away and never lose, are what you know, and how you feel...."

reDEEMed

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Re: Split topic: Purification of morphine sulfate from binding agents
« Reply #2 on: September 08, 2011, 07:24:44 AM »
I have since found that the endo variety of the ms contins work even better with this procedure. You have to add an additional purification step after drying your water the first time, though. The powder will still be orange and some of the binder makes it's way through, but none of the contin does. The shit clumps up in to nice globs of shit in the solvent layer. So the endos are definitely easier to work with if you happen to have a choice, which I do. I haven't ironed out a really awesome second wash procedure yet, but it wont be hard I just havent spent any time trying anything. Mainly I just wanted to see how the two differed doing them this way. I wont post any more about it since I would be pretty much hated by every person here if pill washers started showing up and asking how to wash their pills.
"Ego is a structure that is erected by a neurotic individual who is a member of a neurotic culture against the facts of the matter. And culture, which we put on like an overcoat, is the collectivized consensus about what sort of neurotic behaviors are acceptable."
— Terence McKenna

Sedit

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Re: Split topic: Purification of morphine sulfate from binding agents
« Reply #3 on: September 08, 2011, 07:35:46 PM »
May I ask WTF pills have to do with this thread at all? Im curious as to why the discussion has gone from hydroxylamine to washing morphine pills.
There once were some bees and you took all there stuff!
You pissed off the wasp now enough is enough!!!

reDEEMed

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Re: Split topic: Purification of morphine sulfate from binding agents
« Reply #4 on: September 08, 2011, 07:58:56 PM »
Well, that was going to be his method of obtaining the key precursor, I thought. And since it was mentioned earlier and the information in error I just thought I'd post my experiences. I'd be glad to delete my posts if OP or the mods want. I'm not real keen on teaching idiots how to wash pills anyway, I just thought Hypnos may need to know for what his buddies are doing. Also, I have suddenly found myself with an interest in the OP's original idea here, so, again, I felt the need to post my experiences so far. Unless he has raw morphine laying around, I dunno.

Don't taze me bro.
"Ego is a structure that is erected by a neurotic individual who is a member of a neurotic culture against the facts of the matter. And culture, which we put on like an overcoat, is the collectivized consensus about what sort of neurotic behaviors are acceptable."
— Terence McKenna

hypnos

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Re: Split topic: Purification of morphine sulfate from binding agents
« Reply #5 on: September 09, 2011, 03:01:10 AM »
 Yeah, I too wondered, but I 'guessed' pretty much the same "reasoning" as above,,and in this day and

age, All things considered,,,, tis not an UNreasonable assumption, that for many, their feedstock

will come in differing ways.....No?    But a worthy one with regards to the information it shares 8) 

And I do enjoy a good solvent extraction :)

 It may not be a bad idea to move this thread, but with another heading,

Something without phrases like pill extraction techniques!!  As also stated above,,
Quote
I'm not real keen on teaching idiots how to wash pills
" Ditto

want---Maybe, Hmmm maybe "Interesting Uses for H2O and  various solvents" ;)

"the two things you can give away and never lose, are what you know, and how you feel...."