Amphetamine is one of the oldest and most infamous drugs. It has been used by academics, junkies, athletes, truckers, and the simply curious. However, many of us steer clear because of discussion of neurotoxicity and long-term dopamine down-regulation. Over time, we inevitably find ourselves conflicted because of the constant stories of how useful it is in motivating and focusing the user.
A particularly interesting study was published just a few years ago by Johns Hopkins (one of the few most respected medical schools in the country):
http://www.ncbi.nlm.nih.gov/pubmed/9365033
It stated that, unlike methylphenidate (Ritalin), amphetamine causes significant and long-lasting reductions in dopamine levels.
So, does anyone have any other evidence that low doses of amphetamine have long-term effects? I'm thinking more of small (5-20mg) doses as opposed to the larger doses used by speed freaks and people chasing a rush. It seems like it could be extremely useful in increasing productivity, but not if it's at the cost of your baseline mental health.
A particularly interesting study was published just a few years ago by Johns Hopkins (one of the few most respected medical schools in the country):
http://www.ncbi.nlm.nih.gov/pubmed/9365033
It stated that, unlike methylphenidate (Ritalin), amphetamine causes significant and long-lasting reductions in dopamine levels.
So, does anyone have any other evidence that low doses of amphetamine have long-term effects? I'm thinking more of small (5-20mg) doses as opposed to the larger doses used by speed freaks and people chasing a rush. It seems like it could be extremely useful in increasing productivity, but not if it's at the cost of your baseline mental health.