I suppose you are aware of the risk of seizures which comes with bupropione? Which rises 10-fold when increasing the dosage from 300mg to 600mg?

Having this said and shed my duty of warning to my experiences:

- As stimulant it is nothing to me, I took doses up to 1g+ without feeling really more awake, I felt still exhausted but could hardly sleep.
- To cease or reduce smoking it is great though. Start with 150mg a day, 300mg after 3 days and 450mg after 6 days, all in the morning. Don´t think about smoking more or less just go on as usual. After two weeks you will smoke less and less, kill cigarettes after one or two puffs and start to feel that cigs are actually really not good in taste and anything. After three weeks it is easy to quit (do this in timews of low stress levels thats understood) if you want to and then just quit. No withdrawal whatsoever. Thats how I know it, ok, I take it for depression but I reduced smoking to 1/3 or 1/5 depending on social activities.
It works basically still the same as in the beginning.
It is just that amph or better dex works so much better for me, except that it is illiigal here and very hard to get by prescription. (Meth is only good for fun from time to time as I dont like tweaking at all).

Great if it has an amph touch for you, I wish I could say the same for me 

And it makes immunoessay type drug-screenings positive on amph (not good test strips and of course not in GC).

But to alter it chemically? Cannot see what sense this makes, it is prescription and not really cheap. Not to talk that I took today a look on our favorite police cooperating auction page and found that I could order there everything needed for making P2P in bulk and cheap from legit shops (and not necessarily using the account on the page). Thats in Europe, sorry my imperialistic friends, regard it as the revenge for McDonalds and EuroDisney
So if altering bupropione nevertheless one has to take really care not to increase the convulsive properties anymore - I am not sure which part of the compound is responsible and I don´t want to find it out and also not others to find out the bad way. So if this new stuff does not promise some serious advantages over Dex for example I think it is not worth the risk. I spent the last year several months very close with an epileptic (not really voluntarily) and now I am scared of seizures (before I did not spend one thought on this possibility). But thats really bad.

good luck and fun with the zybans..
/ORG

450mg/day which I don´t use as long as I get my hands on amph or better dex and face no drug screening (every three months), makes quite a lot of pills (which are full of Bitrex btw, bäh!), but it comes only to about 12g a month but the gram costs me only 14 cent (€). Maybe I at least save them in future and don´t give them away to people anymore who think they quit smoking but never will.... 

But pill extraction! The disgrace! If the neighbors get to know of it nobody will talk to me again! Then I am done! What to do? 

450mg/day which I don´t use as long as I get my hands on amph or better dex and face no drug screening (every three months), makes quite a lot of pills (which are full of Bitrex btw, bäh!), but it comes only to about 12g a month but the gram costs me only 14 cent (€). Maybe I at least save them in future and don´t give them away to people anymore who think they quit smoking but never will.... 

But pill extraction! The disgrace! If the neighbors get to know of it nobody will talk to me again! Then I am done! What to do? 

I agree wholeheartedly, I suffer from sinus (badly at times) and get scripts for Pse - the shame the utter disgrace when the chemist accuses me of using PILLS:'<... I feel like telling them there are better ways of doing things (so please, just give me my fucking Pse and shut the fuck up), but that probably wouldn't be a good move.

Jon, manic states of one or more flavours are about the best I can hope for, with or without medication. I've been diagnosed with BPD, but more recently there is some strong suggestions that PTSD would be the better diagnosis (due to a bucketload of incidents that come with certain territories that I neglected to mention when the shrinks were trying to suss out wtf was happening). We relive shit to learn from it, getting all antsy and fearful about shit that is long since dead and not real anymore is not the right way to deal with it I've learned. But my inability to reach that approach earlier in life may be why I don't sleep (or rest when I do) well, or why I didn't at least. In my case it is simple, when the same thing happens multiple times with the same results, there is no point suggesting it is an anomaly. It is hard wiring, learn to deal with it, learn from it and move forward. That gets rid of a fuckload of dysphoria from medications and life in general.

PS Bitrex, so that is the fucking awful taste I get, aha!

Yeah, it did that for a decade or so... Funny really, I was going round the fucking twist bigtime seeing psychobabblers and the rest, and never thought to connect the symptoms with several truly & seriously fucking traumatic incidents at the beginning of that period (despite dreaming about the fuckers incessantly throughout the entire period)... Big fucking "AHA!!" moment a bit over 18 months ago (since getting hurt), when - while going through a 'princess moment' admittedly - I asked myself "WHY? Why the fuck does this shit keep happening?", fortunately I asked a psychartiste the same question and told her the history and what I thought... I was wrong, but she thought there might be 'some' connection between the history and the outcome. Go figure (till then I thought it was all bullshit)

Ok, we have the news that m-chloroamphetamine (http://bitnest.ca/external.php?id=%257DbxUfY%255BC%2540%251B%2505rz%257F%2519%2505P%255CR%251CU%2540pz%257EQ%2507izA%2540%257F%257F9) is pretty fucking strong (the N-methyl version would be stronger again) and in the references section we'll find that the aqueous stability of bupropion in aqueous/acidic solutions is poor to piss-poor. Now, they all oxidized by running a single-phase, whereas if there were a 2-phase system running, the dione, or the hydroxyketone would both be extracted into it.* In any event, they could be converted into the 3-chlorophenyl2-propanone by known methods. How many grams of this shite do we have lying around between us Org?

* Note I can find fuck all on the actual pharmacology of this drug or the N-methoxy variant, use at own risk. Then again, there are studies that state that the 3-substituted amphetamines are not anywhere near as problematic as the p-substituted analogues at decreasing monoamines in brain and 5-HT depletion (http://www.scribd.com/doc/56762757/Structure-Activity-Relationships-Among-the-Halogen-at-Ed-Amphetamines-1978). In fact the paper suggests that they have little to no effect on 5-HT or Serotonin levels unlike P-CA/P-CMA.

** PS For your information it isn't bitrex, they are formulated with Lysine which accounts for that lovely mercaptan taste.

Time poor my friend, I am currently finishing several subjects for a Masters, in order to proceed to a Masters by Research then perhaps a floppy hat in emergency management (think of it, me lecturing LE). I will get there, right at the moment I'm looking into monomethylation of phenethylamine so I can reduce it with Li/iPrOH/NH₃ and forming the amide with homoanisic acid. Homoanisic acid and POCl₃ are the bugbears of the reaction, the other components should be well and truly worked out (although I intend to try some of the MW variations to see if they are more home-chemistry friendly).