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Author Topic: Crashing out oxycodone from aq.soln?  (Read 92 times)

Tsathoggua

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Crashing out oxycodone from aq.soln?
« on: August 12, 2012, 07:40:39 PM »
Plenty of the other alkaloids of the morphine family, both synthetic and naturally occurring exhibit extremely low solubility in 'tone.

Is it possible to crash oxy (as the HCl salt) out of aqueous solution using acetone? the plan would bee for isolation prior to further acylation using propionyl chloride/carbonate to suck up the liberated HCl(g)

How does this idea sound? might just bee a way to get more mileage out of a limited quantity of oxy.
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QBall

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Re: Crashing out oxycodone from aq.soln?
« Reply #1 on: September 12, 2012, 02:09:03 PM »
I see this is a month old but some food for thought.....

If you are meaning to remove the acetaminophen from standard pills, I have wondered this as well.

You could crush and dissolve the oxycodone/apap in water then filter off the apap (which I have done many times and just drank the water, gross taste but it works)

Next I was thinking you could just salt out the oxy, no need for solvents. Just thinking out loud, could be wrong about being able to salt out the oxy.

Tsathoggua

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Re: Crashing out oxycodone from aq.soln?
« Reply #2 on: September 15, 2012, 01:29:11 AM »
No APAP here, oxycontin 40s are the intended substrate.
Nomen mihi Legio est, quia multi sumus

I'm hyperbolic, hypergolic, viral, chiral. So motherfucking twisted my laevo is on the right side.
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