Hopefully the combined wisdom and experience of the vespiary will educate a fellow wasp, heretofore my enquiry. Have any of the brave and brilliant wasps attempted the modified Benseker reduction of the common benzyl alcohol to the phenylalkane of desire?
Using the EN ligand, in place of the heavily scrutinised solvent more commonly known, to solvate electrons from the earth metals proceeds according to established convention. Clarity of the royal blue solution upon end point (expected 10min at STP) and isolation is perplexingly on the contrary though.
The clarification of the solution does not accrue, even upon allowing several hours and/or heating of the reaction. It only clears upon quenching with several volumes of water.
Of far more concern and heartbreak is that the only extract reportedly obtainable, from both residue and NP extraction/acidification are undesired salts. Aqueous washes of the NP solvent/residue have not remedied this, nor has; introducing the reactant as a salt, dissolution of the residue with dilute aqueous hydrochloric, basification, NP extraction, acidification by gaseous or aqueous proton donors.
My the vespiary guide a troubled but gracious and hopeful wasp.
Using the EN ligand, in place of the heavily scrutinised solvent more commonly known, to solvate electrons from the earth metals proceeds according to established convention. Clarity of the royal blue solution upon end point (expected 10min at STP) and isolation is perplexingly on the contrary though.
The clarification of the solution does not accrue, even upon allowing several hours and/or heating of the reaction. It only clears upon quenching with several volumes of water.
Of far more concern and heartbreak is that the only extract reportedly obtainable, from both residue and NP extraction/acidification are undesired salts. Aqueous washes of the NP solvent/residue have not remedied this, nor has; introducing the reactant as a salt, dissolution of the residue with dilute aqueous hydrochloric, basification, NP extraction, acidification by gaseous or aqueous proton donors.
My the vespiary guide a troubled but gracious and hopeful wasp.