Author Topic: Phenylalanine to amphetamine or N-methylamphetamine  (Read 4475 times)

phaseolus

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Re: Phenylalanine to amphetamine or N-methylamphetamine
« Reply #100 on: March 05, 2013, 08:28:12 AM »
Ah. Well, back to the drawing board.

Thiophenechemist

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Re: Phenylalanine to amphetamine or N-methylamphetamine
« Reply #101 on: April 23, 2013, 01:22:21 AM »
http://127.0.0.1/talk/index.php/topic,3648.0.html

Tosyl aziridines will actually work on phenylalanine too! The ketone must be reduced to the alcohol to form the 2-amino 3-alcohol and it is subject to formation of the aziridine by tosyl chloride

and SHABAM

amphetamine

thiophenechemist