New Strategies for the Hofmann Reaction
Dhananjay S. Rane 8z Man M. Sharma"
Journal of Chemical Technology & Biotechnology Volume 59 Issue 3, Pages 271 - 277, 2004
Abstract
Some new strategies, such as the use of hydrotropes, surfactants,
co-solvent, etc., were applied to the Hofmann reaction of fatty amides to obtain
isocyanates, amines and carbamates. Additionally, some industrially important
aromatic amines were synthesised.
Key words: Hofmann reaction, amides, synthesis of amines, isocyanates, carbamates,
alkylation of carbamates, use of surfactants, hydrotropes, co-solvent.
Note.......this might help get the amide into solution for better amine results
Dhananjay S. Rane 8z Man M. Sharma"
Journal of Chemical Technology & Biotechnology Volume 59 Issue 3, Pages 271 - 277, 2004
Abstract
Some new strategies, such as the use of hydrotropes, surfactants,
co-solvent, etc., were applied to the Hofmann reaction of fatty amides to obtain
isocyanates, amines and carbamates. Additionally, some industrially important
aromatic amines were synthesised.
Key words: Hofmann reaction, amides, synthesis of amines, isocyanates, carbamates,
alkylation of carbamates, use of surfactants, hydrotropes, co-solvent.
Note.......this might help get the amide into solution for better amine results