I would be very cautious about trying to vaporise/smoke MDMA freebase, I advise doing a patch test on a sensitive area of skin, such as the underside of the forearm to test for irritation or burning. DEFINITELY do not try smoking/vaporising mescaline base, its apparently pretty caustic and will burn skin. Not something one wants to happen to one's airways. Tsathoggua sustained some really nasty irritation to his lower airways and throat not so long ago after throwing up for the worst time ever. Not sure what triggered it, some alcohol was drunk, but only two small bottles of 5-6% premixed mojito stuff, which isn't enough to do anything but slake his thirst (absolutely delicious stuff, he might add, he has had the owner of one of the local paki shops start trying to get hold of the larger 70cl bottles)
Might have been the 120-130mg of oxycontin earlier, ground up, dissolved in H2O and delivered ahem...enterally, but given his tolerance as a chronic pain patient thats quite possibly not the case.
At any rate, aspirated a tiny amount, he couldn't breathe properly, he tried waiting it out for a day or two, was pretty well frit to sleep the entire time for fear that he might stop breathing in his sleep. And for a few days after calling the ambulance, then ended up calling for an ambulance at some un-outergodly hour in the morning.
Toady isn't asthmatic, but use of a salbutamol inhaler (quite a few of them left behind after kicking the crowbegotten goatwhore former housemate to the dirt where she belongs, and telling her never to show her vile excuse for a 'face' at his home again) as needed did help him breathe a bit more easily and managed to bring his O2 sats up to 100% (room air)
Wasn't much fun at all, he hates hospitals, and the paramedics saw track marks down both arms, although they were really decent in general and didn't go on a judgmental shitbag-fest like some people would have. A royal pain in his arse though trying to give them a list of his rx meds while barely able to talk, given the length of the list (oxycontin, dihydrocodeine IR and XR, indomethacin, tizanidine, xylometazoline nasal spray, loprazolam, chlormethiazole, gaviscon and pregabalin). And likewise, a pain in the chocolate starfish trying to explain what the track marks were from, as they had never heard of methoxetamine.
Thats the kind of unpleasant its likely to get, or worse, if you try smoking mescaline base. Not sure about MDMA FB, not his sort of drug in the first place, so to bee on the safe side, definately do a skin patch test; either apply a small quantity of MDMA freebase to a sensitive area of skin and watch for irritation or burns, etc. or inflict a prick mark on the upper arm with a clean needle and apply the freebase, watch for itching, development of a wheal around the site and burning/irritation. Better to test first, rather than find out the hard way if by chance it shares similar caustic properties with mescaline freebase, burning the throat and lower airway is bad enough, but skullfucking a bunch of holes in one's bronchi and alveoli, while tripping on mescaline, or going through a bloody rapid MDMA comeup has to be a pretty awful experience. After aspirating that time, Tsathoggua felt as though he was drowning. He would be more comfortable with taking MDA via that route than MDMA, given that a primary amine is less basic than a sec. amine. Ye elder toad deity has not long ago read a fairly detailed summary of arylcyclohexylamines on if he recalls right, bluelight, although he may be wrong on where it came from, this included comments about how they were to smoke/vaporize and as a general rule, those with a secondary amine moiety were much harsher and in some cases more or less unfit for smoking.
Do iceheads ever smoke meth freebase? Presumably if they do, its mainly people who either know a cook, or are in the clan.chem game themselves, given the fact that methamphetamine base is an oil and as such not suited to selling to their junkies in baggies/wraps etc. and harder to handle than crystalline shards of the hydrochloride .
As for a 1g blunt...bleeding bastardlyshite mother of fuck, don't you think that dose is greatly excessive? (or rather, nominally 500mg, if shared equally between two, not that the entire amount is going to bee absorbed, with some just getting toasted)
How often do you use serotonin-depleting drugs? its not just 5HT depletion you need to worry about, thats going to impact memory and cognitive function, and at the levels you seem to be using it at, potentially severely so. Other noxious sequelae include damage of dopaminergic neurons due to oxidative stress from uptake of 5HT via DAT rather than SERT and don't forget that its not just in the CNS that gets flooded with 5HT, but in the periphery also. 5HT2b receptor agonism doesn't seem to be much of an issue acutely with single doses of most drugs, or responsible use, not too frequently (cough cough LOOKS AT JON
) but chronic, frequent activation of peripheral 5HT2b receptors causes cardiac fibrosis, and hypertrophic growth of the mitral valve of the heart, along with vasoconstriction all over the show, and specifically pulmonary vasoconstriction. Thats the same reason why all med formulations containing fenfluramine were pulled completely, such as the well-known phen-fen.
Both MDA and MDMA, aside from releasing large amounts of 5HT which then will of course,activate cardiac/pulmonary 5HT2bRs, are high affinity 5HT2b receptor agonists themselves and have been shown to induce the same sort of cardiopulmonary toxicity that fenfluramine/fen-phen do, see this reference:
3,4-Methylenedioxymethamphetamine (MDMA, “Ecstasy”) Induces Fenfluramine-Like Proliferative Actions on Human Cardiac Valvular Interstitial Cells in Vitro
Molecular Pharmacology June 2003 vol. 63 no. 6 1223-1229
doi: 10.1124/mol.63.6.1223
hxxp://molpharm.aspetjournals.org/content/63/6/1223.long
hxxp://www.nejm.org/doi/full/10.1056/NEJM199608293350901#t=article
Appetite-Suppressant Drugs and the Risk of Primary Pulmonary Hypertension
N Engl J Med 1996; 335:609-616 August 29, 1996
Quote from part of the above article: ''All the patients from the national referral center in France and several Belgian patients were followed, and there was no marked improvement in the condition of those who had used anorexic agents after that use had stopped.''
Abstract only on this one, anyone have access to the full paper? the greedy moneygrubbing babyfuckers want $35.95 just to be able to access the article for one bloody day. IMO shady kike-arse practices like that are contrary to the interests of scientific progress.
hxxp://www.sciencedirect.com/science/article/pii/S016372581100074X
Pharmacology & Therapeutics
Volume 132, Issue 2, November 2011, Pages 146-157 doi:10.1016/j.pharmthera.2011.03.008
Serotonin receptors and heart valve disease—It was meant 2B
Not having a snipe at you mate, not at all, but the amount of MDxx you use is clearly abusive and if you keep on using at these levels, it may well kill you down the line and will certainly damage your heart and lungs. In my view, the 5HT-releasing agent type entactogen drugs should be reserved for the right time and place, with the right people (that is, with the right people for those who associate with other people to begin with of course) and never overdone, aside from the very real potential for serious damage if overused, in my opinion they will lose their value. I see the point of them as being able to see things from a new, fresh perspective, and to work with psychological issues if there are any, empathy for others is one thing, but to lose the gift of empathy for oneself, if the experience becomes old hat, is a tragedy, considering just how valuable a set of emotional/psychological tools the entactogens are. A fresh perspective courtesy of psychedelics or entactogens shouldn't be something just to piss away by the kilo, not down one's own throat at any rate.
Topic: 1 gram mdma freebase on a "blunt" (Read 501 times)
