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Author Topic: propanoyl thc & cannabiol synth. and eval.  (Read 294 times)

jon

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propanoyl thc & cannabiol synth. and eval.
« on: February 03, 2010, 01:01:26 AM »
was extracted from finely ground specimen using soxhlet extrator ipa was good solvent for this.
the resultant residue, upon evaopration, had a greenish black tone; and smelled pleasently aromatic.
this was disssolved in acetone and, 10 moles calculated for total content was added of the propionoc anhydride this was held under reflux for 4 hours.
the rxn soup, was decanted onto pyrex dish, placed atop a double boiler and convection evaped using blowdryer; (sorry i can't afford  roto vap)
this was mixed with tobacco and smoked.

qualitative comments:

onset is graduaul (30 minutes) duration 4-6 hours it has this anxiolytic effect and is more hallucinatory than it parent
shall conduct expirimentation on it cinnomoyl ester as this is this is highly lipophllic.

p.s. most notable was it's  anxyolytic effects.
instead of paranoia, it induced a state of hallcinatory relaxation kind of like mdma wow!!!!
this is a fun drug!!!
« Last Edit: February 03, 2010, 01:04:18 AM by jon »

Vesp

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Re: propanoyl thc & cannabiol synth. and eval.
« Reply #1 on: February 04, 2010, 01:41:01 AM »
Do you have any refs on the activity of "prop THC"? It sounds interesting...
Bitcoin address: 1FVrHdXJBr6Z9uhtiQKy4g7c7yHtGKjyLy

jon

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Re: propanoyl thc & cannabiol synth. and eval.
« Reply #2 on: February 04, 2010, 10:49:48 AM »
none other than my own expiriences it's damn good it tastes sweet too because it's an ester acetone is a great solvent for this pm for pointers if you can't estirify something i don't even waste the bandwith.
the cinnamoyl would be the most lipophillic for cinammic acid anhydride synth pm
the lack of refs means you guessed it! swij is the inventor of yet another novel compound he'll keep 'em comming at you.

Enkidu

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Re: propanoyl thc & cannabiol synth. and eval.
« Reply #3 on: February 04, 2010, 06:41:53 PM »
Quote from: jon on February 04, 2010, 10:49:48 AM
the lack of refs means you guessed it! swij is the inventor of yet another novel compound he'll keep 'em comming at you.

I assume the ROA was oral?

I seriously doubt that this hasn't been made before, but this may be the first reported bioassy on the forums, if it's not already on the hyperlab. (Someone with scifinder, like me, could look up whether it's been administered to man in a clinical setting.) One thing to note is that the hydrolysis of the ester isn't as fast as esters of morphine.

http://en.wikipedia.org/wiki/THC-O-acetate
http://www.bluelight.ru/vb/showthread.php?t=309414&highlight=thc+ester

Naf1

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Re: propanoyl thc & cannabiol synth. and eval.
« Reply #4 on: February 05, 2010, 01:59:04 AM »
This is indeed interesting!

I can confirm you are definitely not the first to prepare what in shorthand would be referred to as I guess THC-O-Propionate.

(WO/2009/099868) PROCESS FOR THE PREPARATION OF (-) -DELTA 9-TETRAHYDROCANNABINOL
http://www.wipo.int/pctdb/ja/wo.jsp?WO=2009099868&IA=US2009032361&DISPLAY=DESC

"[0029] Referring again to Formula 111, in one embodiment, Rb is acyl and 0Rb is an ester group. Suitable ester groups include acetate, propionate, butyrate, trimethylacetate, phenylacetate, phenoxyacetate, diphenylacetate, benzoate, p-nitrobenzoate, phthalate, and succinate."

jon

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Re: propanoyl thc & cannabiol synth. and eval.
« Reply #5 on: February 05, 2010, 05:36:29 AM »
this is way better than thc anxiety zero euphoria good lastss 4-6 hours and only two tokes.
who can argue with quadruppile the potency of thc????

swij's already getting rich
this stuff is sweet literally it has a sweeter taste because it's an ester.
$$$$$$
this stuff has swij floating
ya'll can argue all day.
i don't care i know what's gold.
« Last Edit: February 05, 2010, 05:58:05 AM by jon »

jon

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Re: propanoyl thc & cannabiol synth. and eval.
« Reply #6 on: February 13, 2010, 07:38:44 AM »
back in reality land it's amazing the level of grandiosity swij exhibit's ahhaa! bipolar disorder + euphoric states = super grandiosity.
well he apologizes for the above post because it sounds just too over the top.

hypnos

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Re: propanoyl thc & cannabiol synth. and eval.
« Reply #7 on: May 25, 2010, 03:51:44 AM »
matey it is indeed a relief to see you ARE aware of what a wally you sound like in some of these posts ::)!!! coz knowing you the little bit that i do, comments like this
 
Quote
ya'll can argue all day.
i don't care i know what's gold.
dont do justice to the remarkable bloke/chemist you ARE 8)
                         
Quote
back in reality land it's amazing the level of grandiosity swij exhibit's ahhaa! bipolar disorder + euphoric states = super grandiosity
Code: [Select]
that said, i must say "I CAN relate"..........."euphoric states = super grandiosity"  ;D :D :) ;) :P yep definately know this feeling 8)
"the two things you can give away and never lose, are what you know, and how you feel...."

jon

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Re: propanoyl thc & cannabiol synth. and eval.
« Reply #8 on: May 25, 2010, 04:51:04 AM »
euphoria ahhh yes it's really something, sometimes you feel like icharus and fly too high, others you feel godlike.
its a state of mind the medical community deems a negative side effect.
i can understand why cocaine makes me to generous, mdma makes me say things i should hold close to my chest, feeling too good can have it's consequences.

mumbles

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Re: propanoyl thc & cannabiol synth. and eval.
« Reply #9 on: May 25, 2010, 08:34:27 AM »
Even more interesting shit, awesome work jon.

transient

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Re: propanoyl thc & cannabiol synth. and eval.
« Reply #10 on: September 04, 2010, 05:30:47 PM »
Wicked stuff Jon - respect

jon

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Re: propanoyl thc & cannabiol synth. and eval.
« Reply #11 on: September 04, 2010, 06:19:18 PM »
you all should definitely try it.
it's hard to explan one thing i remember is the euphoria grandiosity and zero anxiety i think it would put a hurt in the legal pot brownie business for sure.

roofies44

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Re: propanoyl thc & cannabiol synth. and eval.
« Reply #12 on: September 04, 2010, 07:23:10 PM »
could one try this with acetic anhydride?

jon

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Re: propanoyl thc & cannabiol synth. and eval.
« Reply #13 on: September 04, 2010, 08:40:57 PM »
yes soxlet it into acetone and reflux the acetone extract with acetic anhydride works well.
mek better it's less polar and boils higher for a hotter reflux.
« Last Edit: September 04, 2010, 09:48:27 PM by jon »
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