mdp2p and p2p ?differences of these?

Essential · Sun Aug 21, 2005 9:58 pm

I hope im in the right forum for this post. If not please move me.

Ive was looking at the "complete book of ecstacy". Heres what i read""

Piperonylacetone
2-propanone, 1-(1,3-benzodioxol-5-yl); 2-propanone, 1-(3,4-methylenedioxybenzene); 3,4-methylenedioxyphenylacetone; methyl piperonyl ketone; MDP2P
Boiling point 2 mmHg/108-12°C, 11 mmHg/154-6°C, 22mmHg/166-7°C (also reported 168°C @ 17 mmHg); Molecular weight 179 g/mole

Piperonylacetone, a listed precursor, is used in some of the higher yielding and more common methods for MDMA and it's structurally similar compounds. Several methods are given in the chemical literature for preparation of piperonylacetone with varying yields and staring materials. Phenylacetone which is structurally closely related to piperonylacetone is prepared by these same methods and many others which could be applied to piperonylacetone's synthesis. ""

Wikipedia has mdp2p listed as ""

MDP2P
From Wikipedia, the free encyclopedia.

MDP2P is a phenylacetone that has the IUPAC name 3,4-methylenedioxy phenyl-2-propanone. It is most commonly used in the clandestine synthesis of MDMA, more commonly known as "Ecstasy."

Im looking for a synth without essential oil and was thinking something like
benzyl chloride to phenylacetic acid to phenyl 2 propanone , and then using the peractetic acid synth by chromic. But that wont work cause it looks like i need essential oil to do the whole synth. and if i started with essetial oil the intermediate would give me mdp2p instead of p2p.

Which brings me back to my question again, What is the difference from P2P and MDP2P.

I d like to see if i can use Chromic's peracetic acid synth. This question of mdp2p and p2p keeps coming up and id like to get some info.

Thanks ...

Radiumhero · Sun Aug 21, 2005 11:44 pm

Omg before attempting a synth doesent care of wich kind -> learn more about chemistry esp. organic chemistry well what the 2 names already say on the Mdp2p
there is a methylendioxy group attached to 3rd and 4rth C atom ....
well little bit clumpsy formulated .-.. just look at some drawings ...

biobrew · Sun Aug 21, 2005 11:53 pm

go online, buy a cheap o-chem book that just got passed up by a new edition. spend a month reading the chapters in succession.

take an asprin

and give the good doctor a call inthe morning

Essential · Mon Aug 22, 2005 2:52 am

yea thanks i wasnt looking for criticism but some help. I think weve all started at the bottom and move up. Obviously some people are more ahead than i am. I know that MD-P2P has the methyldioxy group attached and P2P doesnt. Thats the easy part.

I was looking for a little more backround info on mdp2p and p2p. Is it harder to make MDP2P. Can i make MDP2P using phenylacetic acid ...like for instance...how mould i add the methylendioxy group to P2P. I understand that i might not be using the correct terminology but i still want to learn. Is the sythesis of P2P used primarily to make ampetamines or other drugs or are both MDP2P and P2P used to make similiar things.

Does anyone know where maybe i can find FAQ to some of my rather technical questions. For some reason i seen to be confusing MDP2P and P2P. Theres just so many initials.

I Have the 243meg Rhodium archive saved locally to look at for reference. Maybe someone can suggest i look for specific articles to better answer my questions.

Any help would be appreciated, and Biobrew what book do you think i should look for. Should i get just a basic Organic chem book.

Thanks Essential

fcknut · Mon Aug 22, 2005 2:59 am

Seriously, if you're going to ask for help of this kind on an advanced synthetic chemistry forum, you have to expect a certain amount of criticism. To be honest with you, I'm surprised you didn't get a lot more...

your initial question sounded like you didn't know the difference in structure between the two compounds you mentioned, and consequently people have picked up on the rather basic nature of this question. Have a good look and a think about the structures of these two molecule and you should be able to answer your own questions on their respective uses...

That said, I wouldn't want to discourage you from learning a little chemistry - go and buy the imaginatively titled "organic chemistry" by Clayden, Greeves, Warren and Wothers published by the OUP for an excellent introduction to the subject

Essential · Mon Aug 22, 2005 3:08 am

Thanks fcknut
Ill take a look at the book you mentioned.

Thanks Again
Essential

Essential · Mon Aug 22, 2005 3:16 am

I do have to apologise since i thought the basic chemistry forum was limited to INORGANIC chemistry. I then read more about the other forum and found that most people tend to ask more inorganic chemistry questions but this forum is not limited to this type. So i apologise for my childish question and will be moving anymore basic questions to that forum.

Man what a way to start

I am done posting

Thanks and sorry
Essential

hAzzBEEn · Mon Aug 22, 2005 9:10 pm

SWIh thinks reading Total Synthesis II by Strike could help you with your question. It is specifically about the synthesis of amphetamines from P2Ps. It outlines several different ways to arrive at different P2Ps. It does a fair job of comparing the two and how to arrive at the two using the same reactions.

The reason SWIy could be confusing the two is that they can be synthesized in the same manner (different starting material) and can both be reduced to final products in similar ways. Some methods are more suited to MDP2P and some more suited to P2P.

AFAIK, MDP2P cannot be synthesized from P2P. If XTC is the desired product, then MDP2P is the desired precursor. If methyl amph. or just amph. is desired, then P2P is the desired precursor.

SWIyou weren't wrong to ask the question. It would have been an acceptable question for the "General Chemistry" forum. No worries, SWIh was confused about the categories at one point in time, too.

biobrew · Tue Aug 23, 2005 3:16 am

Vitriodor · Thu Aug 25, 2005 3:08 am

java · Consumer

I tried to follow Rhodium's logic for labeling his pdf's as to wheather label as reactions or type of compounds or as author articles.....I hava hundreds of citations that I fear try to organize any more than type of compound in reactions....even tried to do a file organizing....but not enough clarity as which route to take.... so they remain as a large archive daring me to organize......java