Nitromethane and benzaldehyde ?

Elementary · Wed Apr 20, 2005 7:29 pm

What would I get if I condensed nitromethane with benzaldehyde instead of nitroethane ?

mk-1 · Thu Apr 21, 2005 1:58 am

just to continue a long time tradition... UTFSE!
ud get the nitrostyrene....

IndoleAmine · Dreamreader Deluxe

And upon reduction just plain useless phenethylamine...

brain · Linguist Extraordinaire

not so useless !! bigger dosages(50-90%), but fealing somet think like amphetamine !

IndoleAmine · Dreamreader Deluxe

Phenethylamine is the "active" ingredient in... CHOCOLATE! (no joke!) Laughing

Nicodem · Sat Apr 23, 2005 12:59 am

brain · Linguist Extraordinaire

did you try it personally? i did, and i feeled effects - not placebo Smile

... maybe its personal reaction or something like that, but not sure.

IndoleAmine · Dreamreader Deluxe

Yeah, chocolate works for me too, everytime. 100% no placebo... Mr. Green

(seriously: maybe it has something to do with your MAOI experiments?)

METHOXY · Tue May 10, 2005 5:27 pm

Beta-phenethylamine itself is only active when smoked or snuffed not by injection nor by mouth. This explains why Shulgin found no activity. Both active methods are painful and possibly sensitise or otherwise damage the tissues they expose. The stimulation and euphoria produced are pleasant but mainly cerebral. Dose >100mg in a softhead gave noticeable euphoria for 30 minutes and some stimulation for two hours.

Elementary · Tue May 10, 2005 7:13 pm

Can't that phenylethylamine be converted into phenylacetic acid some way ? Or am I getting my alpha and beta muddled up ?

Elementary · Wed May 11, 2005 2:19 am

Done a bit of research on the condensation of benzaldehyde and nitromethane and found a very interesting patent (US2146060)

This patent describes a method of making hydroxylamine hydrochloride and Mandelic acid.

Both these chemicals are useful to the clandestine chemist, mandelic acid as a route to phenylacetic acid and hydroxylamine hydrochloride for forming oximes that can be reduced to amines.

The patent, in brief :-

Benzaldehyde and Nitromethane condensation catalysed by potassium hydroxide in a suitable solvent such as toluene, this gives us the potassium salt of phenylnitroethanol.

The free nitro-alcohol is then obtained via acidification.

Phenylnitroethanol is then hydrolysed with hydrochloric acid in a sealed vessel at a temperature of 110c.

Through simple separation techniques Mandelic acid and Hydroxylamine hydrochloride are obtained.

Please read the patent for full details

loki · guinea pig

phenethylamine, activated by the use of a MAO-B inhibitor (selegiline) did not produce effects anything like ----, in my opinion, the only passing similarity was an extension of the period of alertness. there may have been a hint of hypertension too. methedrine activity does not directly interact with phenethylamine activity, i don't know if human studies of this effect have been done. studies with spider monkeys has been done and 'intermittent recognition of -----like activity' was found at about 30mg/kg phenethylamine but a 30-fold increase in activity was found with complete (either 10 days selective or with a high unselective dose of selegiline, an IRREVERSIBLE MAOI - ie dangerous at unselective doses because of a two week recovery time of MAO) inhibition of MAO-B before dosing (parenterally). the informal one-off test done that i did on myself was with decomposed phenylalanine and although it kept me awake it was not actually like methedrine at all (and by the way, euphoria is reduced in cocaine, and seemingly in methedrine from unofficial testing, and more than likely with anything similar).

i don't think that there is any bioavailability whatsoever of the phenethylamine in chocolate anyway (except in the case of mao inhibition). theobromine is a nicer alkaloid (more euphoric) than caffeine, but there is significant caffeine in chocolate too.