Help to make 1,5-dibromopentane (Method). for PCP

[Chemical_brain]

magnesium organometallicderivative of 1,5-dibromopentane
gives PCP. The only difficulty in this route is the preparation of
the dibromopentane Grignard reagent,
Reaction of N-benzoylpiperidine with the lithium or magnesium
organometallic derivative of 1,5-dibromopentane gives PCP. The only difficulty in this route
is the preparation of the dibromopentane Grignard reagent, with its strict requirement for
anhydrous conditions (Method ?).

[Rhodium]

Ring opening of tetrahydropyran with HBr, or bromination of 1,5-pentanediol with HBr (or red P + Br2).

http://rhodium.lycaeum.org

[Chemical_brain]

It is possible something more About red P+Br2  and TGF+HBr
the description of process.

[Rhodium]

Check out www.orgsyn.org - there should be several ether and alcohol brominations in Organic Synthesis.

http://rhodium.lycaeum.org