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Synthesis of Ergot Alkaloid Precursors

Started by jonah3, April 26, 2000, 07:42:00 PM

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jonah3

Synthesis of Ergot Alkaloid Precursors

Stage 1: Esterification

https://www.thevespiary.org/rhodium/Rhodium/hive/hiveboard/picproxie_docs/000127160-file_igvo.gif" title="View this image">

Stage 2: Batcho - Leimgruber indole synthesis, Step 1

https://www.thevespiary.org/rhodium/Rhodium/hive/hiveboard/picproxie_docs/000127160-file_67w2.gif" title="View this image">

Stage 3: Batcho - Leimgruber indole synthesis, Step 2

https://www.thevespiary.org/rhodium/Rhodium/hive/hiveboard/picproxie_docs/000127160-file_mkh6.gif" title="View this image"> 

Reference: J. Org. Chem., 1980, 45, 3350.