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amphetamine synth possible meth

Started by Kefka, January 20, 2004, 07:30:00 PM

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Rhodium

No, that procedure is plain silly. A reductive alkylation of PEA/HCHO would give N-methyl-PEA (Ph-CH2-CH2-NH-CH3) not alpha-methyl-PEA  (amphetamine).


Kefka

what is the difference between N-methyl-PEA (Ph-CH2-CH2-NH-CH3) and alpha-methyl-PEA  ?

Rhodium

That the added methyl group becomes placed ON the nitrogen, rather than on the carbon atom next to the nitrogen (to create an unbroken three-carbon chain).