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Phenethylamine via Leuckart

Started by psycosmo, May 06, 2002, 10:40:00 PM

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psycosmo

Anybody see any reason why phenethylamine couldnt by made from phenylacetealdeyde use the Leukart Reaction with formamide and formic acid?

Rhodium

Phenylacetaldehyde polymerizes easily, and the Leuckart reaction involves high temperatures and harsh reaction conditions, so it is very possible that the yield from such a reaction wouldn't be especially appealing.