no no you should leave the 14-hydroxycodiene alone and esterify it at the 14 position.
the propionoxy ester 18 times more powerful than morphine the cinnamyl ester 118 times more powerful than morphine.
it's akin to the bently compounds all your doing is exteding a certain part of the phenantherene nucleus with a lipophilic group cinnamyl happens to be the most.

bullshit dichromates oxidize it at the benzylic c-10 carbon and leave you with a mess, opiate chemistry is much more complex than you think it is.
substitution at the 14 position leads to increased euphoria just look up the effects of oxymorphone.
another thing i have made 14 propionoxy7,8dihydrocodienone and it is'nt as potent as the unsaturated version sar relationships in opiates can't be understood on paper it just does'nt work that way.

try it out and see for yourself
i've already seen lab notes of this being attempted by competent chemists
and nothing would crystalize.
patents are notouriously obfuscated.

well maybe the process he ran was run under different conditions what are you actual yeilds?
 i believe in the failed processes a stronger acid was used so that may be the sticking point, i don't know.
i'll show you a paper that says it does'nt work but, i'm not going to scour the net looking for those notes.
you did'nt say what your yeilds are, neither did the paper.
is that a coincedience?

now your contradicting yourself first you said you used dichromate only now your'e saying you used h2o2 sucessively i'm getting more confused all you did is cite some half baked shite on rhodium i'm telling you i have solid evidence it does'nt work one a report of a trial and another on a paper dealing with transitional metal oxidations of codiene directly to 14-hydroxycodienone i would'nt be asking these questions if i did'nt know what i'm talking about

Lets stay focused on the science, no need for personal attacks.

let me explain to you why this does'nt work there has to be a diene system on ring D for oxidation to occur at the 14 position the rearrangement occurs under basic conditions or sometimes slightly nuetral conditions due to keto enol tautomerism.
this can't happen in acidic conditions the intermediate is known as neopinone.

Starting from 10 grams of Codeine base, I obtained approx 5 grams of 14-hydroxycodeinone (or maybe something else but the quantity was 5g). After a 5% Pd/c hydrogenation of 7,8 bong, and an acid/base extraction, I obtained nearly 4,5gr of Oxycodone sulfate.

That's speculations because I don't know if the intermediate is or not 14-hydroxycodeinone and if the final product is Oxycodone.

Finally, concentrated Oxycodone in water solution was drop on a QuickScreen Oxycodone test cassette . After 10min, the result was positive.


edit : the positive answer from The oxycodone test was just an information. 'Cause it could be any other compound nearly close to oxycodone. But that test won't be positive for a concentrated codeine solution, that's a good point ^^


Coincidence ? I THINK NOT !


Have a good day

Why not do a mp test to supplement your results?  More indication to the certainty of your product is necessary, providing information as fact without verification is misleading and will likely cause some headaches for others.

just run some tlc plates there has been no reference of that working in the literature i saw a few examples of it in in chem abs but it did'nt yeild 14-hydroxycodeinone it yelded some quirky dimer.