Author Topic: 4-ho-tryptamine into 4-ho-dmt?  (Read 1450 times)

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trade_om

  • Guest
4-ho-tryptamine into 4-ho-dmt?
« on: July 15, 2004, 05:46:00 AM »
Hello.
Is going from 4-Hydoxy-Tryptamine into 4-Hydroxy-DiMethylTryptamine possible via any of the routes used to go from tryptamine into dmt? as in this -

https://www.thevespiary.org/rhodium/Rhodium/chemistry/tryptamine2dmt.html

?
Or is this completly impossible because the link between the HO molecule and the Carbon is too weak and will break when subjected to this kind of synthesis route?

hest

  • Guest
kjiuyh
« Reply #1 on: July 15, 2004, 06:14:00 AM »

4-Hydoxy-Tryptamine into 4-Hydroxy-Tryptamine


huu ???
But yess, iff you have some 4-OH-tryptamine (lucky bastard) you can use the method in the link.


Lego

  • Guest
They use the benzyl protected 4-OH-indole
« Reply #2 on: July 15, 2004, 07:05:00 AM »

Post 127141

(ejlmp: "Psilocin in 5 steps", Tryptamine Chemistry)


By which method you want to synthesize the 4-hydroxy-indole?


trade_om

  • Guest
I guess that the one who will choose to follow
« Reply #3 on: July 15, 2004, 08:40:00 AM »
I guess that the one who will choose to follow this reaction would like to purchase the 4-hydroxyindloe from a supplier.

Lego

  • Guest
Whoops
« Reply #4 on: July 15, 2004, 09:41:00 AM »
Sorry, 4-hydroxy-tryptamine was meant of course....

Purchasing 4-hydroxy-indole/tryptamine is no good idea (in Lego's opinion) for two reasons:
1) the price
2) it is quite suspicious


Try unsubstituted tryptamine first....


trade_om

  • Guest
I wonder what would be the effects of 6-ho-DMT
« Reply #5 on: July 15, 2004, 09:55:00 AM »
I wonder what would be the effects of 6-ho-DMT if this compound was ever synthesized...

Rhodium

  • Guest
Hard to focus on one topic at a time, eh? ;-)
« Reply #6 on: July 15, 2004, 12:33:00 PM »

"It is pretty generally accepted that 6-HO-DMT is inactive. I am not too surprised. There are so few things with open and exposed hydroxyl groups that succeed in making it through the lipid barriers to the brain."



Alexander Shulgin in

TiHKAL

(http://www.erowid.org/library/books_online/tihkal/tihkal03.shtml#6-HO-DMT)


Lilienthal

  • Guest
Beside that 4-OH-tryptamine is quite ...
« Reply #7 on: July 15, 2004, 12:57:00 PM »
Beside that 4-OH-tryptamine is quite sensitive, especially even under slightly basic conditions. You would want to protect the hydroxy first with an apropriate group.