Methcathinone help.

a-SalviaLover · eating chemicals

I'm planning to try the synthesis of methcathinone via oxidation of ephedrine with KMnO4. The problem is that I was unable to find pure ephedrine without other ingredients. The post profitable source contains ethylmorphine(50 mg ephedrine has 20 mg ethylmorphine). Would KMnO4 oxidize it sth poisonous or harming the Cat. Here's etgylmirohine's structure"

10x in advance!

64bandil · Busy Bee

How about steam distilling the ephedrine out of there? Im positive the opiate wont follow.

squiddler · Tue Jun 28, 2005 3:15 am

You won't find pure ephedrine very readily. Use psuedo E (more readily obtainable) and clean using any of the methods posted elsewhere. It is the GAKKs listed as inactive ingredients that will screw up the reaction. Find a pillstock that contains only psuedo as the active ingredients and as few inactives as you can. Besides it seems like a waste of ethylmorphine (not sure but this may have other possibilities).

loki · guinea pig

yeah pseudoephedrine will work just the same, chirality on the beta carbon is lost in the oxidation just as it is in the reduction. pseudoephedrine sulphate pills often only contain povidone gak which can be removed with a chlorinated hydrocarbon (a dry one of course) and I'm pretty sure that it will oxidise the same as the HCl

a-SalviaLover · eating chemicals

The problem is that I don't seem to find pseudo as an active ingredient either. There is always sth else. The preparation with ethylmorphine is the chepest thing i could Find. Ii is a cough syrup and I was planning to do an acid-base extraction on it. I don't have the appropriate devices for steam distillation. And I don't care about the ethylmorphine as long as it doesn't turn into sth that could kill you.

a-SalviaLover · eating chemicals

I forgot to ask..

What is the difference of the methcathinone produced from ephedrine and from pseudoephedrine? In my opinion the one from ephedrine should be more potent but I could be mistaken.

joe_aldehyde · huxleys associate

pseudoephedrine and ephedrine differ in the configuration of the benzylic carbon atom. upon oxidation they will yield the same product. what you mean is norephedrine vs. ephedrine/pseudoephedrine.

loki · guinea pig

benzylic and beta carbon are synonyms in a phenethylamine

pseudoephedrine is used in nasal decongestant preparations

a-SalviaLover · eating chemicals

I know that, but would the presence of ethylmorphine (or some other sh*t) spoil the reaction or would it produce sth poisonous or spoiling the high. Pls note that with every 350 mg ephedrine, there are 140 mg ethylmorphine. If so how can they be separated and ephedrine purified without using some exponsive and hard to find machinery as distilling machine.

loki · guinea pig

ethylmorphine will not extract under the same conditions as ephedrine in an acid base extraction, it will become sodium ethylmorphinate, which is water soluble.

a-SalviaLover · eating chemicals

Well, I think this is great. This means that only ephedrine would pass through the naphta! Smile

Swyi is surely starting to make it!

a-SalviaLover · eating chemicals

BTW what is the best non-polar solvent, in which ephedrine base is best soluble. Would naphta do the trick, or would swyi have to seek for sth like toluene?

loki · guinea pig

naptha is not the greatest at dissolving amines, gotta use like 3-5x as much... but bearing that in mind, yes naptha can be used.

a-SalviaLover · eating chemicals

What's the best non-polar solvent that can be used?

loki · guinea pig

toluene, xylene