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loki
guinea pig
Joined: 09 Mar 2005
Posts: 391
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Tue Jul 05, 2005 4:30 pm
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octanol isn't hexane or heptane or toluene tho. why the hell did they decide to use octanol for those things anyway is beyond me. surely hexane would be a more useful number considering octanol is not insignificantly soluble in water.


Physical Properties of Pseudoephedrine (d-Ephedrine)
Manske & Holmes, The Alkaloids, Vol III, p 347, Academic Press (1953)

The base forms white rhombic crystals, mp 118°C (from water) and is much less soluble in water than ephedrine. Hydrochloride, colorless needles, mp 181-182°C, the salt is soluble in chloroform. Hydriodide, rhombic crystals, mp 172°C (43).

l-pseudo-Ephedrine has not been found in nature. The base has mp 118-118.7°C. The hydrochloride has mp 182-182.5°C. The l-pseudo-ephedrine-d-tartrate has mp 178°C; l-pseudo-ephedrine-l-tartrate, mp 178.5°C (17, 68, 69, 70).

dl-pseudo-Ephedrine (racemic pseudo-ephedrine) melts at 118°C. The hydrochloride has a mp of 164°C.
References

[17] Ann 470, 157 (1929)
[43] Helv Chem Acta 13, 3 (1930)
[68] Monatsh 41, 319 (1920)
[69] Ber 58, 197 (1925)
[70] Ber 58, 1268 (1925)
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loki
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Joined: 09 Mar 2005
Posts: 391
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Tue Jul 05, 2005 4:32 pm
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oh look at that too:

Quote:
The base forms white rhombic crystals, mp 118°C (from water) and is much less soluble in water than ephedrine. Hydrochloride, colorless needles, mp 181-182°C, the salt is soluble in chloroform. Hydriodide, rhombic crystals, mp 172°C (43).
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a-SalviaLover
eating chemicals
Joined: 15 Jun 2005
Posts: 25
725.68 Points

Wed Jul 06, 2005 1:09 am
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I think Swyi is going to try use the second preparation (the one with pseudoephedrine sulfate) but I don't know whether this would happen or not, cause I've no idea who this person is! Smile


Is there anything that might need a change in the plan if we consider the fact that it 's a sulfate salt. (what base should better be used, what should we have in mind etc..)
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