Jon...you are already patently insane:P
Salat...interesting you say your hubby can chew through benzos. I'm the same. Valium, chlordiazepoxide, temazepam and lorazepam, the relatively speaking, weaker end of the benzo scale, I would likely get, from a two-week script (standard procedure here is to rx for short periods only, up to 14 days, if must, up to 1 month) of 5mg diazzies, maybe 2 or three doses, not looking for recreational use, just for sleep.
I have always, as long as I can remember, had trouble sleeping. I suspect that its an adrenergic thing, possibly, although of course, such a prediction is only an educated guess, it isn't as if one can magically measure levels via microdialysis and other such techniques (and of course I wouldn't try, self-trepanning and insertion of cannulas, microdialysis probes, cementing them in with dental cement is something I need like a hole in the head. Chances are I would handle it better than I do dental work though:P)
Just going from piloerection, jittery overstimulation identical to that produced by drugs or conditions resulting from their use that are known to case a flood of catecholamines, very low or nonexistent appetite when thats happening and I don't take any tizanidine.
I see another mention of the latter drug. Hallucinations? I've had some strange experiences on it, such as a sort-of lucid dream state, being much more aware than usual during a dream, along with talking out loud, and apparently saying some really strange fucking things:P
I find it works best as a sleep aid plugged. It WILL knock you out cold. Doesn't take much to do it either. Plugged tizanidine has even put me out during a stimulant experience, several times. At the tail end of AMT, when all thats left is muscle relaxation, a warm glow, sensory tactile enhancement and tiredness, although insomnia from the amphetamine-like properties of the drug, depending on dosage preventing sleep. Or when I started to notice cognitive deficit relating to sleep deprivation after dosing desoxy following staying up all night reading journal articles on cognitive neuroscience, org.chem, various molecular biology topics and going through the name reaction pages on wikipedia, to broaden my knowledge. Started noticing that ability to concentrate and focus, as well as my already problematic memory were beginning to get poor (or poorer), so I could stay up a while longer reading, I took a low dose of desoxy (500mcg initially, plugged, and redosed a while later with another small dose, typical doses for desoxypipradrol around 2-4mg, its strong fucking stuff, although subtle enough to be dangerous if you don't know what to expect from a pretty clean DARI. doi: 10.1177/0269881111430733
J Psychopharmacol December 7, 2011 0269881111430733 stating that a 7fold peak increase in electrically evoked DA release, 4 times greater than that our good ol' charlie, and extension of the half-life of DA by 15 fold, compared with 5fold using coke as a standard. Its also very, very long acting, which seems to have led on many occasions to people thinking they could treat it like they do other stimulants, giving the drug a bad name, redosing compulsively will just lead to several weeks of psychotic sleep deprivation almost certainly, due to its extreme half-life)
When I got tired of it, not of continuing to read, but of the desoxy, as I am really no fan of stimulants, as they are just not my thing. I took a couple of sleepers, chlormethiazole, I think and waited for them to kick in, then dosed some 20mg of tizanidine rectally (this is a large dose, be well aware of how you respond to the drug before dosing that sort of level, esp. rectally, and avoid if you have low BP) and couldn't even finish my rollup before it knocked me out cold. It acts damn fast plugged and even a small dose, 4mg is enough to induce sleep within a few minutes.
I find it a very effective anxiolytic, taken sublingually. I don't have a clinical anxiety problem, but to help deal with situations causing it, I'll take 2-4mg under the tongue beforehand, works a treat.
I take it daily, as a preventer med for overloading of the autie variety, although it works for that acutely as well as a prophylactic. In a sense, by analogy, sort of like how asthma inhalers (not that autism is a disease like asthma of course) come in two main types, preventers and rescue inhalers, the former being long acting and taken regularly to stop an asthma attack and a fast-acting, shorter lasting rescue inhaler for stopping attacks once one has started.
Being that its similar to clonidine, although shorter acting and some 40x less potent as a hypotensive agent (presumably due to differences in potency at imidazoline receptors between the two drugs), and clonidine being rx'd in PTSD, to help deal with hyperarousal (I find it helps to an incredible degree with nightmares, I almost never get any at all on tizanidine). Having PTSD also, might be something of use to you Salat?
What is tianeptine like subjectively? I would like to try it, if only out of interest, as its a strange drug, pharmacologically speaking. Although I wouldn't know where to get it, at least not to the best of my knowledge.
Tryl, what info on krokodil do you have that suggests its not desomorphine (or rather, an assortment of byproducts and noxious shite that can't have been cleaned much, if at all, given the short duration of action of the tiny amount of desomorphine they get left with (the russian junkies) and the time it takes to prepare (around 1.5 hours and 90 minutes respectively according to the testimony of recovered addicts) Tianeptine is stated to have a half life of 2.5 hours on wikipedia though, putting the two into around the same ballpark figure for duration of action.
The krokodil preparation being desomorphine rather than tianeptine makes more sense to me, looking at the tissue damage resulting from IV use, it doesn't look gangrenous, tissue isn't blackened, but rather, the result of frank necrotic death of exposed tissue. Desomorphine must be quite something, if its that reinforcing, enough to make a junkie with his necrotic radius/ulna showing, and the flesh of his forearm stripped of flesh right down to the bone.
Given the known method of preparing krokodil, and reagents used in manufacture, red P, thionyl chloride, I2, naptha, acids and bases, and it being doubtful the users could clean it up much in the way of a post-reaction workup, not to mention that I just bet they aren't exercising much in the way of PH control of the final witches brew of nasties I think it fits, in terms of likely effects on injection.
Apparently the average lifespan of a junky that starts using krokodil is usually less than 2 years. I've read it said that every hit takes a year off your life, I'd dismiss such a statement out of hand when said of most drugs as propaganda in the war on drug user, seeing as how it always is. But I can well believe it in this case. I read an article just yesterday about a young woman who had managed to kick it in an missionary-operated xtian facility, although she went back to it, and had to do it all over again. This woman had escaped the massive tissue damage that goes with krokodil, but was left with severe motor function deficit as well as pronounced neurological problems, which speaks against it being tianeptine in my view.
) again there were no negative effects experienced, HOWEVER, when combined with a drug that raises seretonin levels, and clonazepam, which used to be a favored maintenance drug for epileptics (at 2-4mg pd) AND THEN STOPPING someone with elevated seretonin levels cold, off 8mg of clonazepam, IS ASKING FOR SEIZURES! 
Once again your mystical metabolism saves the day 
tianeptine_PTSD.pdf