Hey, there is probabaly some obvious answer to this question. I'm just wonder is it possible to isomerise safrole using an equimolar amount of NaOH rather than the standard KOH. I'd assume there would be a reduction in yeild, but would it still isomerise? Sorry if this is a stupid questions!

Correct on both fronts. NaOH may be used. NaOH will reduce yields compared to KOH.

That's perfect thanks! I just wanted be sure! I'll give the NaOH isomerisation a go!

I cannot say for sure but I really doubt the hydrochloride salt is soluble in acetone. The hydroiodide should be though.

What is piece of glassware that bubbles steam through a solution in steam distillation called?

Generally it's called the steam inlet tube:

https://the-collective.ws/forum/index.php?topic=14825

 

http://www.google.com.tw/patents/about?id=jp0aAAAAEBAJ

The methods here are probably your best bet.

Reaction of the amine with methyl formate gives a formamide. Further reaction of the formamide with dimethyl carbonate gives a methyl carbamate, and pyrolysis gives an isocyanate. The resulting isocyanate can react with benzyl alcohol to give Cbz-protected amines or with tert-butanol to give t-BOC protected amines. If you're using this for what I think you're using it for, t-BOC is what you're after, since it will stand up to any base you can throw at it, including butyl-lithium.

You might be able to get away with isopropanol instead of tert-butanol if you really can't get tert-butanol, but it's not really a suspicious chemical at all I don't think. t-butanol is also formed by decarboxylating beta-hydroxy beta-methylbutyrate aka HMB.

t-BOC anhydride isn't very suspicious either, but it could get suspicious fast if the rxn works.

Is it possibly methylbenzene aka. Toluene?

http://www.meta-synthesis.com/chemthes/entity_datapage.php?id=446

I could really do with some help identifying an aromatic oil .I'm just starting to learn about identifying unknown substance but realize its going to take me a while to do.

READ THE RULES:

http://127.0.0.1/talk/index.php/topic,369.msg3325.html#msg3325

yep it is tolly,

phenyl ring with a methyl group attached = toluene

thanks! i have never seen ph used in the notation system.. is that an old system? using ph in notation?

i would look for something like a shortened methylbenzene

It's a very common abbreviation for phenyl

Perfect, best of luck with them, some of the reagents are kinda stange all right!

Looks like you might lose some Dimethylamine when bubbling through the NaOH solution. With a solubility of 354g/100mL in water it might be more than you'd like. Just a thought. Otherwise the idea seems sound.