DCM is toxic being turned into Carbon monoxide as stated. Toluene is turned into benzoic acid and Xylene into Terephthalic acid. The later two metabolites are alot less toxic but I think it comes down to responsibility of use. Don't Huff them, any of them. If you notice DCM makes you sick then odds are so is Toluene and Xylene just in a different fashion.

DCM is my favorite solvent and even though Emulsions can be a bitch a little NaCl and a vibrating plate normally will break this with little issue. I use it because its non flamable, Cheep, It is a bottom puller so it is less prone to Emulsion forming when doing a small scale operation, Very powerful and slightly polar solvation abilitys, and the main effect is it evaporates with little effort. A simple warm water bath is all thats needed to evaporate DCM quickly and cleanly.

When a strictly non-polar is truely needed I would with out a doubt go with Xylene over Toluene for two reasons. Toluene is a bitch to get where im at and Toluene is more prone to Emulsions. If I need a very, Very clean seperation where solvation ability is of little concern and I need to remaining solvent to be as easy to dry as possible I go with Naptha. I hate the smell of Naptha and the variations of boiling point but it does have some benifits.

Never really used it but I would think its effects would be simular to DCM. Being denser it may be slightly more resistant to emulsions but I don't really know.

Does anyone know why chloroform is so much more expensive?  It's easy as piss to produce.

The main question would be the synthesis is alpha methyl tryptamine.

There is a synthetic method for tryptamine from indole-grignard with aziridine in diethyl ether, followed by a hydrolysis (1).

If the aziridine is replaced by 2-methylaziridine than two possible products cold be obtained, at once, indole-3-(2-amino)-1-propane and indole-3-(2-amino)-2-propane:


What would be the compound what would be produced in higher percent?

And another question: does anyone know a synthesis for: 5-(2-Aminopropyl)indole (5-IT)

Why is it that I can't find any bioassays of the Oxazoline derivative of MDA, IE: The aminorex variation with a methylenedioxy bridge. I have checked chemspider and Pubchem and have not even returned someone trying to sell me the compound or any thing suggesting it exist.

Any information on it?

Im pretty sure its biological activity would be simular to MDA albeit longer lasting and slightly less potent then MDMA. This would be idea yet for some strange reason it seems no one ever synthesized it. Why?

AMT would be the major product, though I don't know exact percentages.  You'll just have to figure that out yourself

Does anyone have a link to the discussion on this?

I have a hard time taking someones word for it since I don't know if they even made it correctly. I want to see the discussion on it and come to a conclusion that way. If it was one person saying it was no good then im not convinced. I need more bioassays from various sources before I call this one busted. Everything about the compound seems to suggest to me that it would be a general longerlasting replacement for MDA if nothing else a suppliment to extend an MDA experience.

Look at this
http://en.wikipedia.org/wiki/3',4'-Methylenedioxy-%CE%B1-pyrrolidinopropiophenone
And then suggest that Oxazoline variation would not be active. I know this compound is a bit removed from Oxazoline but I hope you see where im comming from.

So can anyone explain why in your standard lysergic acid hydrolysis you dissolve the mixed LSA's in basic methanol and evaporate before the hydrolysis in aqueous basic solution?

Is platinum oxide a watched chemical?

Friend of mine found small but very old bottle full of paspalic acid on university.
I highly doubt anyone else knows that it even exists.

How much is is worth!?